Friday, May 4, 2018
Primary sclerosing cholangitis
Primary sclerosing cholangitis (PSC) is a chronic liver disease characterized by cholestasis ,caused by progressive inflammation and scarring of the bile ducts of the liver. This inflammation impedes the flow of bile to the gut, which can ultimately lead to liver cirrhosis, liver failure and liver cancer.
The left image shows a histologic specimen demonstrating chronic inflammation surrounding the bile duct.